منابع مشابه
Azathioprine shock.
Azathioprine has been used as an immunosuppressant for over 20 years in cancer chemotherapy, organ transplantation and diseases with confirmed or suspected immune mechanisms. A hypersensitivity reaction manifesting as fever, rash, myalgia and a neutrophil leucocytosis occurring about 2 weeks after exposure is well documented and has been confirmed by challenge testing. Hypotensive reactions are...
متن کاملAzathioprine-induced shock.
sufflation in peripheral vascular disease. The gas, from 100 to 400 ml, is injected directly via an arterial catheter, the site depending on the angiographically demonstrated arterial supply to the limb. I have reserved the method mainly for those who are not suitable for angioplasty and in whom surgery is not contemplated. Twenty-one such patients, with generally severe and widespread disease,...
متن کاملAzathioprine hypersensitivity presenting as cardiogenic shock and Sweet's syndrome in a patient with microscopic polyangiitis.
Azathioprine hypersensitivity is a clinical syndrome which may manifest from isolated fever and rash to multi-organ failure. This rare condition is usually self-limiting following the discontinuation of azathioprine. Therefore, it is important to maintain a high index of clinical suspicion for hypersensitivity reactions with azathioprine therapy. We report a case of azathioprine hypersensitivit...
متن کاملAzathioprine-induced shock in a patient suffering from undifferentiated erosive oligoarthritis.
Shock due to a hypersensitivity response to azathioprine is unpredictable, occurs seldom and bears a potentially fatal outcome. Azathioprine is widely used in the treatment of autoimmune diseases and in solid organ transplantation. Here, we present a patient who suffered from undifferentiated erosive oligoarthritis and was treated with azathioprine. This patient developed anaphylactic shock whi...
متن کاملCorticosteroids – Azathioprine
Fifteen years ago, classical immunosuppressive therapy was inconceivable without corticosteroids and azathioprine. A large number of transplantees administering these drugs had successful immunosuppression and good function of the graft over longer period of time. Nevertheless, side-effects of corticosteroids to cardiovascular system (hypertension, congestive heart failure, thrombophlebitis), t...
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1986
ISSN: 0032-5473
DOI: 10.1136/pgmj.62.729.677